Article Abstract

Increased lipid desaturation and ovarian cancer stem cells

Authors: Thomas W. Grunt, Peter Valent


Epithelial ovarian cancer is still the most lethal gynecological
malignancy (1-3) with an overall 5-year survival rate of
<50% (4). This is particularly troubling considering the fact
that preclinical research over the last couple of years led to
significant advances in our general understanding of cancer
biology, which spurred the development of numerous novel
anti-cancer drugs.