The emerging landscape of lncRNAs in diabetic nephropathy

Xiaoyun He, Chibin Pu, Chunlin Ou, Suxian Zhou

Abstract

With the acceleration of global aging, the incidence of diabetes mellitus (DM) is significantly increasing and is accompanied by a significant increase in the incidence of diabetic nephropathy (DN), a major complication of diabetes. DN is the leading cause of end-stage renal disease (ESRD) in DM, with a prevalence of 20–40%, and is the major cause of death and disability in DM patients (1).