The guanine nucleotide exchange factor VAV2 as a new prognostic parameter in adrenocortical carcinoma

Deborah Cosentini, Sandra Sigala, Elisa Saba, Elisa Roca, Alfredo Berruti

Abstract

Adrenocortical carcinoma (ACC) is an aggressive and extremely rare malignancy with an estimated incidence of 0.7–2.0 cases/million/population/year (1).