Article Abstract

Are lung adenocarcinoma mutations shaping the immune microenvironment?

Authors: Philippe Rochigneux, Edward B. Garon


Recently, Biton et al. published in Clinical Cancer Research the article “TP53, STK11 and EGFR Mutations Predict Tumor Immune Profile and the Response to anti-PD-1 in Lung Adenocarcinoma” (1). This article points out the challenging question of the interplay between tumoral mutations in lung adenocarcinoma (localized and metastatic) and the composition of immune microenvironment.