Significance of indocyanine green test in radiotherapy for hepatocellular carcinoma

Photon radiotherapy was originally not commonly used for hepatocellular carcinoma (HCC) because the large irradiation volume could lead to radiation-induced liver disease (RILD). According to a phase I study by Kim et al., a dose of EQD2 ≥78 GyE¹⁰ was necessary to achieve local control.