Significance of indocyanine green test in radiotherapy for hepatocellular carcinoma

Masashi Mizumoto, Yoshiko Oshiro, Hideyuki Sakurai


Photon radiotherapy was originally not commonly used for hepatocellular carcinoma (HCC) because the large irradiation volume could lead to radiation-induced liver disease (RILD). According to a phase I study by Kim et al., a dose of EQD2 ≥78 GyE10 was necessary to achieve local control.