Discernable differences in the genetic and molecular profile of cerebellar glioblastoma

Muhibullah S. Tora, D. Cory Adamson


Glioblastoma (GBM) represents the most common primary malignancy of the central nervous system in adults. While the vast majority of GBMs are supratentorial lesions (S-GBM), 0.9% to 3.4% of GBMs occur in the cerebellum (C-GBM) (1-3). Considering this rarity, relatively few studies have examined C-GBMs specifically and the majority of these studies have been understandably limited by small patient populations.