Stereotactic ablative radiotherapy for oligometastatic breast cancer in elderly patients

Ignacio Morales-Orue, Juan Zafra-Martin, Laura Garcia, Rodolfo Chicas-Sett, Juan Castilla-Martinez, Maria Auxiliadora Cabezon, Javier Burgos, Marta Lloret, Pedro C. Lara


Breast cancer (BC) is the principal cause of cancer-related death in women. Metastatic patients are usually treated with a systemic therapy, but clinical results are limited. Oligometastatic subjects can benefit from high-precision radiotherapy techniques to potentially achieve a complete response. Currently, there is limited evidence of stereotactic ablative radiotherapy (SABR) treatments in elderly oligometastatic cancer patients. A review of the medical literature was performed in PubMed database to assess the current role of SABR in the treatment of breast oligometastases in elderly patients. SABR represents a feasible and safe therapeutic approach in oligometastatic elderly BC patients. Further studies are required to establish the optimum patient selection and treatment scheme.