Analysis of The Cancer Genome Atlas data to determine the correlation between AGO2, TERT, and TERC in various cancers

Soo-Jung Jung, Jae-Ho Lee


We read with great interest the article by Laudadio et al. (1) regarding the role of AGO2 in telomere biology; their study asserted that AGO2 regulated telomerase activity through the control of the association between TERT and TERC in the assembly of active telomerase ribonucleoprotein.