Clinomics—an underutilized resource?

Biochemical recurrence after radical prostatectomy for prostate cancer can be seen in 30–50% of the cases depending on stage, PSA and Gleason score. About 50% of the recurrences become apparent within 2 years after surgery with local failure being the predominant pattern. It is therefore obvious that early post-operative adjuvant radiotherapy (ART) or PSA-triggered salvage radiotherapy (SRT) are frequently considered in these patients and improve outcome. Open questions regarding the optimal mode of treatment at biochemical recurrence especially the combination of radiotherapy with antihormonal therapy and/or other systemic agents are currently investigated. In addition current studies demonstrated the value of dose-escalated SRT especially in patients with R+ disease (1).