Commentary


Fat talks: a new role for adipose tissue in promoting prostate cancer in obesity

Matthew J. Watt, Renea A. Taylor

Abstract

Why is it that obese men have more aggressive prostate cancer and die faster from their cancer compared with lean men? This question has remained largely unanswered, but a recent study by Laurent and colleagues (1) has provided one possible explanation: chemokine signals from prostate-associated fat cells directly communicate with cancer cells to promote local dissemination.

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