Fat lure: adipocytes attract cancer cells out of the prostate

Alexandra M. Blee, Haojie Huang


Although the majority of prostate cancer (PCa) cases are now detected and treated at early stages, PCa remains the second leading cause of cancer death in American men (1). In the case of more advanced tumors, androgen deprivation can prevent cancer progression temporarily, but this inevitably leads to castration-resistant prostate cancer (CRPC).