Vol 6, Supplement 10 (December 14, 2017): Translational Cancer Research (Focused Issue: Precision Dosing of Targeted Anticancer Drugs)

Preface

Preface to Precision Dosing of Targeted Anti-Cancer Drugs

Andrew Rowland, Michael J. Sorich

PDF Pages: S1498-S1499 Full Text (2032) COI Form Open Access

Review Article

Precision dosing of targeted anticancer drugs—challenges in the real world

Hannah Yejin Kim, Jennifer H. Martin, Andrew J. Mclachlan, Alan V. Boddy

PDF Pages: S1500-S1511 Full Text (10508) COI Form Open Access

Role of pharmacokinetic modeling and simulation in precision dosing of anticancer drugs

Adam S. Darwich, Kayode Ogungbenro, Oliver J. Hatley, Amin Rostami-Hodjegan

PDF Pages: S1512-S1529 Full Text (13398) COI Form Open Access

Circulating cell free deoxyribonucleic acid for tracking early treatment response and disease progression in advanced cancers

Akash Rathod, Ashley Hopkins, Andrew Rowland, Michael J. Sorich

PDF Pages: S1530-S1540 Full Text (3235) COI Form Open Access

Role of pharmacogenetics in personalised imatinib dosing

Daniel T. Barratt, Andrew A. Somogyi

PDF Pages: S1541-S1557 Full Text (6967) COI Form Open Access

The role of ethnicity in personalized dosing of small molecule tyrosine kinase inhibitors used in oncology

Josephine A. Touma, Andrew J. McLachlan, Annette S. Gross

PDF Pages: S1558-S1591 Full Text (4956) Open Access

Role of CYP3A4 in kinase inhibitor metabolism and assessment of CYP3A4 activity

Gerd Mikus, Kathrin Isabelle Foerster

PDF Pages: S1592-S1599 Full Text (4328) COI Form Open Access

Original Article

Physiologically-based pharmacokinetic modeling as an approach to evaluate the effect of covariates and drug-drug interactions on variability in epidermal growth factor receptor kinase inhibitor exposure

Madelé van Dyk, Andrew Rowland

PDF Pages: S1600-S1612 Full Text (3852) COI Form Open Access

Combination of small-molecule kinase inhibitors and irinotecan in cancer clinical trials: efficacy and safety considerations

Ganessan Kichenadasse, Arduino Mangoni, John Miners

PDF Pages: S1613-S1623 Full Text (3579) COI Form Open Access

Disclosure:

The supplement “Precision Dosing of Targeted Anticancer Drugs” was commissioned by the editorial office, Translational Cancer Research without any sponsorship or funding. Andrew Rowland and Michael J. Sorich served as the unpaid Guest Editors for the supplement.