Guest Editor: Catherine T. Frenette, M.D., Scripps Center for Organ and Cell Transplantation, Scripps Clinic, USA
Hepatocellular carcinoma (HCC) ranks among the most common cancers worldwide, and is one of the leading causes of cancer-related death. Worldwide, there are more than 600,000 cases of HCC every year, and the 5 year mortality is nearly 90%. Treatment of HCC is complex, and involves understanding of the cancer as well as the underlying liver disease. This special issue of Translational Cancer Research serves as a review of all issues surrounding diagnosis and treatment of hepatocellular carcinoma.