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The value of pre- and post-contrast-enhanced ultrasound in evaluation of malignant potential of gastrointestinal stromal tumors

  
@article{TCR17109,
	author = {Ning-Yi Cui and Rui Zhang and Xiao-Li Feng and Shuang-Mei Zou and Li-Shuang Gu and Xuan-Tong Gong and Jie Han and Yong Wang and Ke Lv},
	title = {The value of pre- and post-contrast-enhanced ultrasound in evaluation of malignant potential of gastrointestinal stromal tumors},
	journal = {Translational Cancer Research},
	volume = {6},
	number = {6},
	year = {2017},
	keywords = {},
	abstract = {Background: Contrast-enhanced ultrasound (CEUS) permits evaluation of intratumoral vascularity in real time. The purpose of the present study was to compare the performance of conventional ultrasound (US) and CEUS in the evaluation of malignancy risk in patients with gastrointestinal stromal tumors (GISTs). 
Methods: In this retrospective study, we included patients with suspected GISTs who underwent conventional US and CEUS preoperatively. Fifty patients with pathologically confirmed GISTs were enrolled. Tumor risk stratifications were determined according to the 2008 NIH criteria. Pre- and post-CEUS findings were reviewed. Tumor size, lobular border, heterogeneity, cystic areas, calcification and intratumoral gas on US, irregular vessels, heterogeneous enhancement, and non-enhancing areas on CEUS were compared among different risk groups of GISTs. The relationship between time-intensity curve parameters and risk stratification was also analyzed. 
Results: Larger lesion size, lobulation, and cystic areas were associated with higher risk (P0.05). Visualization of intratumoral irregular vessels and non-enhancing areas on CEUS were significantly correlated with higher risk classification (P},
	issn = {2219-6803},	url = {http://tcr.amegroups.com/article/view/17109}
}