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Tumor-mesenchymal stem cell interactions: therapeutic implications for epithelial ovarian cancer

  
@article{TCR21743,
	author = {Alain Piché},
	title = {Tumor-mesenchymal stem cell interactions: therapeutic implications for epithelial ovarian cancer},
	journal = {Translational Cancer Research},
	volume = {1},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {Epithelial ovarian cancer (EOC) is the most common cause of gynecological cancer-related death (1). When compared to most solid tumors, EOC has a distinct mechanism of dissemination. Cells detach from the primary tumor and aggregate in peritoneal fluid to form free-floating multicellular spheroids, which then travel through the peritoneal fluid at distant sites onto the mesothelial lining where metastatic outgrowth occurs (2). Because this process is clinically silent, most women (~70%) present with metastasis throughout the peritoneal cavity.},
	issn = {2219-6803},	url = {http://tcr.amegroups.com/article/view/21743}
}