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The efficacy of postoperative radiotherapy for locally advanced rectal cancer without neoadjuvant therapy

   
@article{TCR22695,
	author = {Dehao Yu and Yu Wang and Yongxi Song and Peng Gao and Jingxu Sun and Xiaowan Chen and Yaoyuan Hu and Zhenning Wang},
	title = {The efficacy of postoperative radiotherapy for locally advanced  rectal cancer without neoadjuvant therapy},
	journal = {Translational Cancer Research},
	volume = {7},
	number = {4},
	year = {2018},
	keywords = {},
	abstract = {Background: The 2018 guidelines for treatment of cancer by site recommended by the National Comprehensive Cancer Network (NCCN) does not include a specific treatment recommendation for rectal cancer patients who did not receive preoperative chemoradiotherapy. The study objective was to evaluate whether postoperative radiotherapy was effective for such patients.
Methods: Survival was evaluated in 9,585 patients who underwent surgical resection for stage II or III rectal cancer and were registered in the Surveillance, Epidemiology, and End Results-Medicare database between 1992 and 2009. Overall survival (OS) benefit in propensity score (PS)-matched patient cohorts were estimated by Cox proportional hazards models.
Results: After stratification by chemotherapy regimen, the difference in OS of stage III patients between the no-treatment and radiotherapy groups was significant (P},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/22695}
}