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Is re-radiation for glioblastoma after progression associated with increased survival: to treat or not to treat?

   
@article{TCR25233,
	author = {Jose A. Carrillo and Santosh Kesari},
	title = {Is re-radiation for glioblastoma after progression associated with increased survival: to treat or not to treat?},
	journal = {Translational Cancer Research},
	volume = {8},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {Glioblastoma is the most common malignant brain tumor, representing 53.8% of all gliomas (1). Despite standard of care treatment with radiation and temozolomide chemotherapy, glioblastoma has a dismal prognosis with median survival of 14.6 months (2) and 20.9 months with addition of tumor-treating fields (Optune) (3). After tumor progression, treatment with re-irradiation and/or systemic therapy has yet to show improved overall survival leading to disagreement as to the best management of the patient who has progressed after standard of care treatment.},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/25233}
}