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Development and validation of a polygenic hazard score for aggressive prostate cancer identification

  
@article{TCR25668,
	author = {Nihal E. Mohamed and Ashutosh K. Tewari and Kamlesh K. Yadav},
	title = {Development and validation of a polygenic hazard score for aggressive prostate cancer identification},
	journal = {Translational Cancer Research},
	volume = {8},
	number = {Suppl 2},
	year = {2018},
	keywords = {},
	abstract = {Prostate cancer (PCa) is a major health issue that affects over a million men globally every year (1). Although screening men for PCa using prostate specific antigen (PSA) estimates, over the past three decades, resulted in a significant improvement in quantity and quality of life, two major problems reduce the value of early screening using this method: (I) inaccuracy of test results (i.e., the receipt of false positive results), and (II) unnecessary aggressive treatment for low-risk PCa that could be managed via active surveillance or observation (2).},
	issn = {2219-6803},	url = {https://tcr.amegroups.org/article/view/25668}
}