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Microarray-based differential expression profiling of long noncoding RNAs and messenger RNAs in formalin-fixed paraffin-embedded human papillary thyroid carcinoma samples

  
@article{TCR27752,
	author = {Hui-Xian Yan and Jin Du and Jing Fu and Wei Huang and Li-Meng Jia and Pang Ping and Ling Zhao and Ye-Qiong Song and Xiao-Meng Jia and Jing-Tao Dou and Yi-Ming Mu and Fu-Lin Wang and Wen Tian and Zhao-Hui Lyu},
	title = {Microarray-based differential expression profiling of long noncoding RNAs and messenger RNAs in formalin-fixed paraffin-embedded human papillary thyroid carcinoma samples},
	journal = {Translational Cancer Research},
	volume = {8},
	number = {2},
	year = {2019},
	keywords = {},
	abstract = {Background: Long noncoding RNAs (lncRNAs) can regulate the expression of genes at almost every level. The altered expression of lncRNAs was observed in many kinds of cancers. Until recently, few studies have focused on the function of lncRNAs in the context of papillary thyroid carcinoma (PTC). 
Methods: In the current study, we collected seven PTC and nodular goiter tissue samples and explored mRNA and lncRNA expression patterns in these samples by microarray. 
Results: We observed aberrant expression of 94 lncRNAs and 99 mRNAs in the seven PTC samples as compared to the nodular goiter tissue [fold change (FC) ≥2.0; P},
	issn = {2219-6803},	url = {http://tcr.amegroups.com/article/view/27752}
}