@article{TCR9303,
author = {Zhen-Yu He and Xun Li and Qing-Shuang Chen and Jia-Yuan Sun and Feng-Yan Li and San-Gang Wu and Huan-Xin Lin},
title = {Elevated serum carcinoembryonic antigen and CA15-3 levels and the risk of site-specific metastases in metastatic breast cancer},
journal = {Translational Cancer Research},
volume = {5},
number = {5},
year = {2016},
keywords = {},
abstract = {Background: To assess the relationship between serum carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels and the risk of site-specific metastases in metastatic breast cancer.
Methods: Clinicopathological characteristics of patients diagnosed with metastatic breast cancer at two academic centers between 1998 and 2013 were retrospectively analyzed. The association between serum CEA and CA15-3 levels at systemic recurrence and site-specific metastases was investigated by univariate and multivariate analyzes.
Results: A total of 305 patients were identified. One hundred and thirteen (37.0%) and 139 (45.6%) patients showed elevated serum CEA and CA15-3 levels, respectively. Serum CEA levels were less frequently elevated in patients with triple negative disease (P=0.030). Furthermore, elevated serum CEA (P=0.002) and CA15-3 (P},
issn = {2219-6803}, url = {https://tcr.amegroups.org/article/view/9303}
}