Charles Limoli, PhD, Professor
Department of Radiation Oncology, University of California, Irvine, CA, USA
Dr. Limoli received his BS degree in chemistry from MIT then went on to receive his PhD in Biomedical Sciences from UCSD. Following a postdoc at UCSF, he received his first academic appointment at that institute where he stayed for 12 years before coming to UCI in 2006. Since that time Dr. Limoli’s research has focused on radiation effects in the CNS, where he has defined many of the mechanisms that contribute to radiation-induced cognitive dysfunction. His work has since defined the importance of oxidative stress in the brain, how irradiation disrupts neuronal structure and synaptic integrity and how stem cells can be used to offset the adverse effects of both radio- and chemotherapy in the brain. Continued work strives to further understand the causes, consequences and potential remedies for neurocognitive dysfunction caused by various cancer treatments.