Mansoor M. Ahmed, PhD

Radiotherapy Development Branch (RDB), Radiation Research Program (RRP), Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute/National Institutes of Health, Rockville, MD, USA

Dr. Mansoor M. Ahmed received his Ph.D. from University of Madras in Environmental Toxicology studying the cytogenetics and molecular biology of pesticides induced myelodysplastic syndrome in farmers from South India. He had his post-doctoral training at Thomas Jefferson University and University of Kentucky studying micro-dissection of chromosomes in solid tumors and radiation-induced signal transduction respectively. He had his first faculty position appointment at Department of Radiation Medicine, University of Kentucky, where he established molecular radiation biology program. After his full-tenure at University of Kentucky, he then later joined Weis Center for Research at Geisinger Clinic and later to Department of Radiation Oncology, University of Miami, whereby, he established programs in Molecular Radiation Biology.

His major research focuses involved employing various novel strategies with the goal of increasing the therapeutic ratio through two broad areas: (1) the manipulation of tumor control by modulating the processes that control cell cycle and apoptosis; and (2) the reduction of normal tissue morbidity by applying the emerging information on the molecular mechanistic basis of radiation or chemotherapeutic sensitivity. He has a major interest in how best to apply fractionation schemes from a mechanistic standpoint. His translational pre-clinical research on low-dose radiation as a chemo-potentiator resulted in the development of novel clinical protocols for head and neck, pancreas, ovarian and lung cancers. He joined Radiation Research Program in March 2012 covering portfolio of grants in signal transduction, bio-markers, cancer stem cells, immune modulation and in-vitro & in-vivo models in radiotherapy.