Giusi Irma Forte, PhD

Institute of Molecular Bioimaging and Physiology (IBFM), Cefalù Support Unit (U.O.S), National Research Council (CNR) – Laboratory of Oncologic Technologies (LATO), Cefalù, Italy

Dr. Giusi Irma Forte is currently responsible of the “Genomics and cell Methodologies” laboratory at the Cefalù Support Unit of IBFM-CNR, an institute that has a main site in Milan. In Cefalù, their research activities are carried out at the laboratories of the public-private company LATO (LAboratory of Oncologic Technologies), based at the San Raffaele-Giglio Hospital (HSR). The IBFM-LATO diagnostics and research activities are strongly translational, with the overall objective of cancer studying and care, using advanced biomedical technologies involved in pathology, proteogenomics, biomedical imaging (Nuclear Medicine PET/CT, SPECT/CT, MRI), Intraoperative Radiation Therapy (IORT) and Magnetic Resonance-guided Focused Ultrasound, (MRgFUS). Their research team is young and is composed by physicists, biologists, engineers, doctors, who work together, ensuring the convergence of multidisciplinary expertise on the issues under study.

At this time, in her laboratory, the main biologic research activities regard the studying of biological effects of ionizing radiations and high/low intensity ultrasounds, by proteogenomic approach, for the achievement of protocols inducing selective tumor cell apoptosis. To this aim, a separate or synergic use of radiation and ultrasounds are hypothesized. Particularly, as ultrasounds are able to enhance the cell surface permeability, appropriated drug delivery systems are also studied. Final goal is to develop new therapeutic strategies of personalized cancer care.