TY - JOUR AU - Wu, Jiazhu AU - Shi, Huidong PY - 2017 TI - Unlocking the epigenetic code of T cell exhaustion JF - Translational Cancer Research; Vol 6, Supplement 2 (March 31, 2017): Translational Cancer Research Y2 - 2017 KW - N2 - T cell exhaustion is one of the hallmarks of cancer and chronic viral infections. Revitalization of exhausted T cells is critical for restoring immune function and curing diseases. Recent studies suggest that epigenetic mechanisms are directly involved in the transcriptional control of T cell exhaustion. Decoding the epigenome specific to exhausted T cells is a pivotal step toward development of therapeutic approaches for overcoming T cell exhaustion in infections and cancer. UR - https://tcr.amegroups.org/article/view/12604