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Association between radiosensitivity and molecular subtypes in patients with early-stage breast cancer and lymph node-negative status

  
@article{TCR17768,
	author = {Sung-Hsin Kuo and Chiun-Sheng Huang},
	title = {Association between radiosensitivity and molecular subtypes in  patients with early-stage breast cancer and lymph node-negative  status},
	journal = {Translational Cancer Research},
	volume = {6},
	number = {S9},
	year = {2017},
	keywords = {},
	abstract = {Previous studies have reported that the use of radiotherapy (RT) following breast conserving surgery (BCS) had similar clinical outcomes when compared with that of mastectomy (1,2). The Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), which performed a meta-analysis of 10,801 breast cancer patients’ data obtained from 17 randomized trials comparing RT with no RT after BCS, revealed that RT decreased the risk of locoregional and distant recurrences at 10 years, from 35.0% to 19.3%, and subsequently resulted in an increased survival of 3.8% at  15 years. RT also resulted in an absolute recurrence reduction of 15.4% (10 years, no RT vs. RT; 31.0% vs. 15.6%, P},
	issn = {2219-6803},	url = {https://tcr.amegroups.com/article/view/17768}
}