%0 Journal Article %T Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma %A Binder, David C. %A Ladomersky, Erik %A Lenzen, Alicia %A Zhai, Lijie %A Lauing, Kristen L. %A Otto-Meyer, Sebastian D. %A Lukas, Rimas V. %A Wainwright, Derek A. %J Translational Cancer Research %D 2018 %B 2018 %9 %! Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma %K %X EGFRvIII is the most common mutation of EGFR and results in the creation of a tumor-specific antigen that is detectable in 23–33% of human glioblastoma (GBM) (1). EGFRvIII arises due to the deletion of EGFR exons 2–7, which generates a truncated extracellular domain capable of constitutive EGFR activation. %U https://tcr.amegroups.org/article/view/20301 %P S510-S513 %@ 2219-6803