TY - JOUR AU - Sultan Ali, Wael Abdullah AU - Liu, Weixing AU - Xiao, Yuanyuan AU - Fang, Juemin AU - Xu, Qing PY - 2019 TI - A case report of small bowel adenocarcinoma with liver metastases: genetic profiling and clinical management JF - Translational Cancer Research; Vol 8, No 4 (August 31, 2019): Translational Cancer Research Y2 - 2019 KW - N2 - Small bowel adenocarcinoma (SBA) is a rare cancer. Optimal treatment regimens have not been established for SBA. This is due in part to the low disease incidence and subsequently, the lack of large, properly designed, randomized clinical trials. In this study, we present a case of an advanced small bowel adenocarcinoma patient with a prolonged progression-free survival of more than 3 years. Genetic profiling of this patient was used to predict prognosis and guide clinical management of the disease. The patient was treated with bevacizumab in combination with XELOX based on her genetic background and our experience in treating colorectal cancer. This treatment strategy, which was tolerable and effective, may be considered as a viable therapeutic strategy for the treatment of metastatic SBA. UR - https://tcr.amegroups.org/article/view/29537