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Clinicopathologic characteristics and survival analysis in stage IVB cervical cancer with hematogenous metastasis

  
@article{TCR30683,
	author = {Haoran Li and Yufei Yang and Hongyu Zhou and Fei Liu and Mengjiao Li and Lihua Chen and Xiaohua Wu and Xi Cheng},
	title = {Clinicopathologic characteristics and survival analysis in stage IVB cervical cancer with hematogenous metastasis},
	journal = {Translational Cancer Research},
	volume = {8},
	number = {4},
	year = {2019},
	keywords = {},
	abstract = {Background: The purpose of this study was to analyze the clinical characteristics, treatment modalities and prognosis of stage IVB cervical cancer patients with hematogenous metastasis.
Methods: Between March 2005 and December 2017, a total of 160 patients FIGO (International Federation of Gynecology and Obstetrics, version 2018) stage IVB cervical cancer patients with hematogenous metastasis were included in this retrospective study. Patients were excluded from this analysis if they had lymphatic metastasis alone. Survival analyses included the Kaplan-Meier method, log-rank test, and Cox proportional hazards model.
Results: Among 160 patients with hematogenous metastasis, 78 patients (48.8%, 78/160) exhibited only hematogenous metastases, while 82 (51.3%, 82/160) exhibited distant organ and lymph node (LN) metastases. Bone (37.5%, 60/160) was the most frequent metastatic site compared to lung (23.1%, 37/160) and liver (12.5%, 20/160). The median duration overall survival (OS) was 26 months and the 3-year OS rate was 35.3%. In univariate analysis, a significant difference was found in prognostic factors related to OS including tumor size (P=0.030), histology (P=0.006), white blood cell (WBC) count (P},
	issn = {2219-6803},	url = {https://tcr.amegroups.com/article/view/30683}
}