TY - JOUR AU - Perna, Fabiana AU - Sadelain, Michel PY - 2016 TI - Myeloid leukemia switch as immune escape from CD19 chimeric antigen receptor (CAR) therapy JF - Translational Cancer Research; Vol 5, Supplement 2 (August 22, 2016): Translational Cancer Research Y2 - 2016 KW - N2 - Gardner et al. recently reported on two cases of mixed lineage leukemia (MLL) + acute myeloid leukemia (AML) occurring after CD19 chimeric antigen receptor (CAR) therapy for MLL + B-acute lymphoblastic leukemia (ALL) (1). This report provides new insights into mechanisms of immune escape from targeted immunotherapy and strategies to prevent their occurrence with adapted immune interventions. UR - https://tcr.amegroups.org/article/view/9016