Case Report


A rare case of primary spinal peripheral T cell lymphoma presents as type-B symptoms

Guoping Wang, Bin Liu, Xiangyang Liu, Xiongjie Shen, Hongzhe Liu

Abstract

The present study reported a 23-year-old man who presented with fever and low back pain for >1 month. With the exception of a significant rise in CRP and ESR, laboratory examinations following hospitalized revealed no positive finding. Computed tomography (CT) and magnetic resonance imaging (MRI) of lumbar spine with contrast revealed mass lesions at right of the L3–5 vertebra and in epidural at L4, which caused spinal canal stenosis. The present study used a posterior approach to decompression and internal fixation, and excision of the lesion was performed from an anterior approach. Intraoperatively, the lesion was flesh-like without pus. Results of rapid pathological examination reported a round malignant tumor. According to the final pathological examination results, the diagnosis was non-Hodgkin’s lymphoma, unspecified peripheral T cell lymphoma immunophenotype. The patient succumbed to the disease 1-year after the spinal operation, despite chemotherapy with cyclophosphamide, adriamycin, vincristine and prednisolone and local radiotherapy.

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