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Original Article

Transketolase contributes to hepatocellular carcinoma migration, invasion, angiogenesis, and tumorigenesis
Yanxin Li, Guosheng Tan, Shiqiu Xiong, Bing Zhang, Wei Chen, Jianyong Yang, Heping Li
Telomerase reverse transcriptase promoter region mutations and the clinical characteristics of pulmonary neuroendocrine tumors
Chenghui Li, Zhiming Jiang, Qiaoyuan Cheng, Hongyang Lu
Identification of potential gene and microRNA biomarkers for colon cancer by an integrated bioinformatical approach
Qingxia Ma, Jingyi Song, Zhen Chen, Lei Li, Bin Wang, Ningning He
Neutrophil to lymphocyte ratio but not ring enhancement could predict treatment response and new lesion occurrence in patients with hepatocellular carcinoma by drug eluting beads transarterial chemoembolization
Shihong Ying, Xianyong Zhou, Shaolin Gong, Zhiyi Peng
Radiotherapy and radiochemotherapy increase serum levels of pro-inflammatory interleukin-6 and C-reactive protein in patients with head and neck cancers
Dorota Kiprian, Bozena Czarkowska-Paczek, Aleksandra Wyczalkowska-Tomasik, Malgorzata Fuksiewicz, Beata Kotowicz, Leszek Paczek
Clinical efficacies of gemcitabine combined with docetaxel single or plus bevacizumab as second-line therapy for malignant pleural mesothelioma
Chengzhi Zhou, Yinyin Qin, Dehua Zhang, Zhanhong Xie, Xinqing Lin, Jiexia Zhang, Shiyue Li, Rongchang Chen, Nanshan Zhong
Head-to-head comparison of serum and urine cytokeratin-19 fragments (CYFRA 21–1) for bladder cancer diagnosis
Fengwen Fu, Fanchun Zeng, Zhongyi Sun, Fengshuo Jin
Docetaxel-polymeric nanoparticle enhances radiotherapeutic efficacy in human pancreatic cancer
Jin Park, Seok Soon Park, Kyoung Jin Lee, Eun Jin Ju, Seol Hwa Shin, Eun Jeong Ko, Sa-Won Lee, Min Hyo Seo, Jung Shin Lee, Si Yeol Song, Seong-Yun Jeong, Eun Kyung Choi
Cysteinylglycine for potential diagnosis of extrahepatic cholangiocarcinoma using a novel metabolomic approach
Longjiu Cui, Xiaoqing Jiang, Liang Zhao, Yuanzhuo Chen, Zhangjun Cheng, Jiehua Li, Weifeng Tan, Alex F. Chen
Expression of the desmosome-related molecule periplakin is associated with advanced stage and poor prognosis of esophageal squamous cell carcinoma
Kazuhiko Yamada, Teruki Hagiwara, Fumika Inazuka, Takuhito Sezaki, Toru Igari, Chizu Yokoi, Kyoko Nohara, Satoshi Yamashita, Taeko Dohi, Yuki I. Kawamura
Prognostic significance of neutrophil-lymphocyte ratio in multiple myeloma patients
Huaqin Zuo, Lili Zhai, Xu Liu, Hongmin Gao, Peipei Xu
Effects of GLS1 on the epithelial-mesenchymal transition of hepatocellular carcinoma in vitro and in vivo
Yajuan Cao, Binghua Li, Xianbiao Shi, Hongyan Wu, Chen Yan, Ouyang Luo, Decai Yu, Yitao Ding
Prognostic value of NF-κB interacting long non-coding RNA expression in lung adenocarcinoma and lung squamous cell cancer: a study based on the cancer genome atlas datasets
Bohua Fu, Yuzhu Xu, Yi Wang, Huilong Chen, Zhenli Huang, Yinan Hu, Lei Zhang, Guorao Wu, Juan Liu, Yanhan Deng, Yong Mou, Qi Wang, Xuefei Qi, Yu Tao
Prognostic value of miRNA-181a in human colorectal cancer evaluated by in situ hybridization
Shu Lin, Lin Zhao, Xinyue Song, Jing Zhang, Yan Wang, Longyang Jiang, Lifeng Yu, Jia Bi, Minjie Wei
Vitamin D receptor and cyclooxygenase-2 expression in uterine leiomyoma tissues and their correlation
Fujun Liu, Xiao Zhang, Keqin Yan, Jing Liang, Lin Deng, Dingqing Feng, Bin Ling
Enhanced antitumor effect via combination of triptolide with 5-fluorouracil in pancreatic cancer
Wei Wang, Qingling Wang, Linpei Wang, Xinfeng Li, Dexin Liu
Defining the individual internal gross tumor volume of hepatocellular carcinoma using 4DCT and T2-weighted MRI images by deformable registration
Fujing Huang, Changsheng Ma, Ruozheng Wang, Guanzhong Gong, Dongping Shang, Yong Yin
MiR-875-5p inhibits hepatocellular carcinoma cell proliferation and migration by repressing astrocyte elevated gene-1 (AEG-1) expression
Caixia Hu, Shichang Cui, Jiasheng Zheng, Tian Yin, Junsheng Lv, Jiang Long, Wenwen Zhang, Xun Wang, Shoupeng Sheng, Honghai Zhang, Yu Sun, Hongguang Wang, Cong Li
The relative biological effectiveness of proton and carbon ion beams in photon-sensitive and resistant nasopharyngeal cancer cells
Cihang Bao, Yun Sun, Yuanli Dong, Ziyu Le, Lien-Chun Lin, Lin Kong, Jiade J. Lu
A novel scoring system to predict ascites development post hepatectomy for BCLC stage B hepatocellular carcinoma
Hong-Gang Qian, Li-Ying Wu, Cheng-Peng Li, Ang Lv, Jian-Hui Wu, Bo-Nan Liu, Xiu-Yun Tian, Wei Xu, Chun-Yi Hao
An investigative study of factors affecting breast cancer patients’ preference of extended endocrine therapy
Feng Mao, Yan-Na Zhang, Jia-Lin Zhao, Qiang Sun

Review Article

Prophylaxis and treatment of venous thromboembolism in cancer patients: a systemic review and critical appraisal of clinical practice guidelines
Qinchang Chen, Qingui Chen, Xixia Lin, Lingling Li, Yonghui Li, Zhenluan Tian, Wei Liu, Kai Huang
Potential biomarkers to evaluate therapeutic response in advanced pancreatic cancer
Chao Yang, Guopei Luo, He Cheng, Yu Lu, Kaizhou Jin, Zhengshi Wang, Chen Liu, Xianjun Yu

Review Article

Common applications of next-generation sequencing technologies in genomic research
Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis
Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Review Articles

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
Rositsa Dueva, George Iliakis
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer
Deep Kwatra, Anand Venugopal, Shrikant Anant
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Historical perspective and evolution of charged particle beam therapy
Huan Giap, Bosco Giap
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Role of NBS1 in DNA damage response and its relationship with cancer development
Yuichiro Saito, Hiroko Fujimoto, Junya Kobayashi
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Proton therapy for gastrointestinal cancers
Ted C. Ling, Joseph I. Kang, Jerry D. Slater, Gary Y. Yang
Proton therapy for head and neck cancer: current applications and future directions
Alexander Lin, Samuel Swisher-McClure, Laura Bonner Millar, Maura Kirk, Caitlyn Yeager, Ali Kassaee, Boong-Keng Kevin Teo, Stephen M. Hahn
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Original Articles

Comparison of tissue characterization curves for different CT scanners: implication in proton therapy treatment planning
Chee-Wai Cheng, Li Zhao, Mark Wolanski, Qingya Zhao, Josuha James, Kate Dikeman, Michael Mills, Mei Li, Shiv P. Srivastava, Xing Qi Lu, Indra J. Das

Editorial

Focusing in on radiation induced brain injury
M. Kerry O’Banion

Original Article

A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman
Defining functional changes in the brain caused by targeted stereotaxic radiosurgery
Vipan K. Parihar, Munjal M. Acharya, Dante E. Roa, Omar Bosch, Lori-Ann Christie, Charles L. Limoli
A chain reaction approach to modelling gene pathways
Gary C. Cheng, Dung-Tsa Chen, James J. Chen, Seng-jaw Soong, Coral Lamartiniere, Stephen Barnes
Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA
Takashi Kon, Xiuwu Zhang, Qian Huang, Zhonghui Yang, Shanling Liu, Bin Yan, Fang Li, He Wang, Chuan-Yuan Li
Identification of cancer mechanisms through computational systems modeling
Zhen Qi, Eberhard O. Voit
A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman

Review Article

Integrative clustering methods for high-dimensional molecular data
Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley
Sparse principal component analysis in cancer research
Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen
Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications
Louis Dubeau
Cancer biomarker discovery and validation
Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida
The promise and challenge of ovarian cancer models
Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Review Articles

New developments in treatment planning and verification of particle beam therapy
Reinhard W. Schulte, Andrew J. Wroe
Externally modulated theranostic nanoparticles
Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi
Intestinal stem cell injury and protection during cancer therapy
Jian Yu
Cancer stem cells in glioma: challenges and opportunities
Jialiang Wang, Yufang Ma, Michael K. Cooper
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou
Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis
Chang-Lung Lee, Jordan M. Blum, David G. Kirsch
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
DNA double strand break repair via non-homologous end-joining
Anthony J. Davis, David J. Chen
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation
Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase
Lijian Shao, Lixian Wu, Daohong Zhou
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis
Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
Improving chemoradiotherapy with nanoparticle therapeutics
Michael Joseph Eblan, Andrew Zhuang Wang
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Molecular mechanisms involved in tumor repopulation after radiotherapy
Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li
Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules
Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy
Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar
Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma
Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients
Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Original Article

Statistical strategies for microRNAseq batch effect reduction
Yan Guo, Shilin Zhao, Pei-Fang Su, Chung-I Li, Fei Ye, Charles R. Flynn, Yu Shyr

Original Article

Frameless single-isocenter intensity modulated stereotactic radiosurgery for simultaneous treatment of multiple intracranial metastases
Steven K. M. Lau, Xiao Zhao, Ruben Carmona, Erik Knipprath, Daniel R. Simpson, Sameer K. Nath, Gwe-Ya Kim, Jona A. Hattangadi, Clark C. Chen, Kevin T. Murphy

Below are the latest Translational Cancer Research articles published online ahead of print publication.

Original Article


Review Article

Axillary lymph node surgical treatment
Daniela Andreina Terribile, Cristina Accetta, Sabatino D’Archi, Ida Paris, Danilo Di Giorgio, Giorgia Garganese, Simona Maria Fragomeni, Riccardo Masetti

Perspective


Case report


Mini-Review