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Preface on Focused Issue on Translational Imaging in Cancer Patient Care

Preface to 2017 focused issue: Translational Imaging in Cancer Patient Care
Yì-Xiáng J. Wáng, Yong Wang

Original Article on Translational Imaging in Cancer Patient Care

Diffusion kurtosis imaging in assessment of gastric cancer aggressiveness
Changfeng Ji, Yujuan Zhang, Huanghuang Zheng, Ling Chen, Wenxian Guan, Tingting Guo, Qinglei Zhang, Song Liu, Jian He, Zhengyang Zhou
HIF-1α and VEGF levels for monitoring hepatocellular carcinoma treatment response to transcatheter arterial chemoembolization
Kang Liu, Lin Yang, Xiao-Ming Zhang, Yi Zhou, Tao Zhu, Nan-Dong Miao, Yong-Jun Ren, Hao Xu, Xu-Li Min, Juan Peng, Ke Yang, Shi Yang
A pilot study on correlations between preoperative intravoxel incoherent motion MR imaging and postoperative histopathological features of rectal cancers
Chenchen Yan, Xia Pan, Gang Chen, Wei Ge, Song Liu, Ming Li, Ling Nie, Jian He, Zhengyang Zhou
Changes of tryptase in patients with hepatocellular carcinoma after transarterial chemoembolization
Xu-Li Min, Lin Yang, Xiao-Ming Zhang, Yi Zhou, Nan-Dong Miao, Yong-Jun Ren, Hao Xu, Kang Liu, Juan Peng, Ke Yang
Quantitative assessment of liver fibrosis and its stage in a rabbit model by using intravoxel incoherent motion diffusion-weighted imaging at a 3T magnetic resonance system
Fan Chen, Jian-Qiong Yang, Xiao-Ming Zhang, Rui Li, Tian-Wu Chen, Yan-Li Chen, Yu Jiang, Lan Wu
Quantification of solid hypo-echoic thyroid nodule enhancement with contrast-enhanced ultrasound
Xuehong Diao, Jia Zhan, Lin Chen, Yue Chen, Yingchun Liu
The value of pre- and post-contrast-enhanced ultrasound in evaluation of malignant potential of gastrointestinal stromal tumors
Ning-Yi Cui, Rui Zhang, Xiao-Li Feng, Shuang-Mei Zou, Li-Shuang Gu, Xuan-Tong Gong, Jie Han, Yong Wang, Ke Lv
Trans-abdominal ultrasound features of the newly named intraductal papillary neoplasm of the bile duct
Xian-Shui Fu, Meng-Na He, Yan-Xiao Chang, Jing Zhang, Ke Lv, Hua-Bin Zhang, Li Tan, Yu- Xin Jiang
Clinical efficacy of intravenous chemotherapy alone versus intravenous combined with intraperitoneal chemotherapy for newly diagnosed gastric cancer with malignant ascites
Suyun Zhang, Rui Feng, Tao Jiang, Xinli Wang, Zhangchi Pan, Ling Li, Shu Zhang, Qiang Chen, Sheng Yang
Adrenal venous sampling as used in a patient with primary pigmented nodular adrenocortical disease
Xiaoxin Peng, Yintao Yu, Yi Ding, Fang Yang, Xiangshu Chen, Cheng Chang
Abdominal CT protocol’s influence on postoperative follow-up of lesions detection associated with gastrointestinal tumours
Jing-Feng Zhang, Chuan-Gen Guo, Jin-Sheng Liao, Qi-Dong Wang, Bai-Shu Zhong, Jian-Hua Yan
Intravoxel incoherent motion magnetic resonance imaging in assessing histopathological features of gastric cancers: initial findings
Changfeng Ji, Ling Chen, Wenxian Guan, Tingting Guo, Qinglei Zhang, Song Liu, Jian He, Zhengyang Zhou
Clinicopathological and theranostic analysis of 82 breast cancer patients older than 80 years
Qing Lv, Dong Meng, Chunlei Sun, Linfang Jin, Chungen Xing

Case Report on Focused Issue on Translational Imaging in Cancer Patient Care

Herpes simplex encephalitis during radiation therapy in a patient with nasopharyngeal carcinoma
Feng Zhao, Luyi Bu, Wenbao Zhang, Guorong Yao, Xiaokai Yu, Xinke Li, Fang Wang, Xue Jiang, Zhongjie Lu, Senxiang Yan
Magnetic susceptibility artefact on MRI mimicking lymphadenopathy: description of a nasopharyngeal carcinoma patient
Feng Zhao, Xiaokai Yu, Jiayan Shen, Xinke Li, Guorong Yao, Xiaoli Sun, Fang Wang, Hua Zhou, Zhongjie Lu, Senxiang Yan

Original Article

Frequencies of actionable mutations and survival in variants of invasive adenocarcinoma of lung
Zhengbo Song, Tangfeng Lv, Yiping Zhang, Yong Song
miRNA-451 inhibits proliferation and motility of the gastric cancer SGC-7901 cell line via targeting AKT-mediated signal pathway
Biao Chen, Jun-Jian Deng, Wei Ge, Yong-Fa Zheng, De-Dong Cao, Ximing Xu
Integrated formulas to forecast prostate cancer: the parameters of influencing the prostate specific antigen level as an adjunct to prostate specific antigen and multi-parametric MRI to predict prostate cancer before biopsy
Hui Wang, Sheng Tai, Li Zhang, Chaozhao Liang
The tumor-draining lymph nodes are immunosuppressed in patients with hepatocellular carcinoma
Ze-Yu Shuang, Yi-Ze Mao, Yong-Cheng Liu, Guo-He Lin, Jun-Cheng Wang, Jun Wang, Sheng-Ping Li
Diagnostic application of lipidomics fingerprints to bladder carcinoma
Gabriele Cruciani, Roberto Maria Pellegrino, Alessandra Di Veroli, Samuela Cataldi, Daniela Marocco, Elisabetta Costantini, Angelo Sidoni, Mariapia Viola-Magni
Preliminary study on the role of serum PECAM-1 in metastatic breast cancer
Lin-Feng Zheng, Pei Chen, Zeng Wang, Xiao-Jia Wang, Lei Lei
A concise review of current guidelines for the clinical management of hepatocellular carcinoma in Asia
Haowen Tang, Yong Huang, Weidong Duan, Chuan Li, Xuan Meng, Jiahong Dong
Evaluation of clinical efficacy after combinational treatment of esophageal cancer using target artery perfusion of verapamil and chemotherapy
Yabei Liu, Liting Qian, Kelong Ma, Tengyue Zhang, Gaofei Fan, Yang Wu, Tian Li, Pingsheng Fan, Zhaoshen Li
Study the effect of CTSD interaction proteins in invasion and metastasis of nasopharyngeal carcinoma
Weiguo Huang, Yafei Wang, Guqing Zeng, Yufang Yin, Chenjie Ouyang, Yunlian Tang, Yu Li, Gebo Wen, Ailan Cheng
Microarray analysis reveals altered expression of multiple circular RNAs in the pathogenesis of esophageal squamous cell carcinoma
Hao Chen, Bin Zheng, Lin Huang, Wei Zheng, Chun Chen
siRNA-mediated silencing of FOXQ1 expression inhibits cell proliferation and induces apoptosis in human osteosarcoma cells
Hao Wu, Liming Xia
Alteration of non-coding RNAs expression pattern in metastasis process of esophageal squamous cell carcinoma
Shenglan Meng, Jingge Zhang, Longyong Mei, Fuqiang Dai, Zheng Ma
Fractal structure in the volumetric contrast enhancement of malignant gliomas as a marker of oxidative metabolic pathway gene expression
Kai J. Miller, Sharon Berendsen, Tatjana Seute, Kristen Yeom, Melanie H. Gephardt, Gerald A. Grant, Pierre A. Robe
Acute hypoxia induces apoptosis in serum-deprived prostate cancer LNCaP cells
Weiyong Liu, Yunkai Zhu, Jun Jiang, Xuechao Jiang, Yaqing Chen
FL118, a novel anticancer compound, inhibits proliferation and migration of ovarian cancer cells via up-regulation of cytoglobin in vivo and in vitro
Hongqin Zhao, Dong Wang, Zhihong Yang, Lixia Ji, Zhantao Liu, Yuecheng Yang, Qingxia Ma, Xuezhu Lin, Guohui Jiang
Inhibition of ERK signaling potentiates the anti-tumor activity of FL118 on hepatocellular carcinoma cells
Qingxia Ma, Dong Wang, Heng Zhang, Zhihong Yang, Yuecheng Yang, Lixia Ji, Zhantao Liu, Hongqin Zhao, Guohui Jiang
Autophagy blockade enhances the anti-cancer effect of Romidepsin in gastric cancer
Wei-Jian Sun, Bin He, Beng Yang, Wen-Di Hu, Jian Wu, Shu-Sen Zheng
Wip1−/− ameliorates hepatic ischemia/reperfusion injury via PI3K/ Akt activation
Huayu Yang, Chang Li, Wei Huang, Wei Guo, Jingrong Cui, Xinting Sang, Yilei Mao
Expression and significance of EMMPRIN, MMP-9 and TIMP-1 in non-small cell lung carcinoma tissues of Guangxi Province, China
Yongyong Wang, Lei Dai, Mingwu Chen, Lei Xian, Jianji Guo, Nuo Yang
Characteristics and treatment of patients with neuroendocrine carcinoma of the gastroesophageal junction: an analysis of 13 cases
Yingzhi Qin, Chao Guo, Xiaoyan Chang, Yeye Chen, Lei Liu, Jieshi Zhang, Cheng Huang, Zhijun Han, Dongjie Ma, Hongsheng Liu
Serum cytokeratin-18 is a non-invasive biomarker for evaluating disease severity in patients with liver cirrhosis and hepatocellular carcinoma
Huayu Yang, Lejia Sun, Langqing Sheng, Xiaowei Wang, Haifeng Xu, Shunda Du, Haitao Zhao, Xin Lu, Xinting Sang, Yilei Mao

Review Article

Surgical management of colorectal cancer: the Fudan University Shanghai Cancer Center experience
Yuchen Wu, Fangqi Liu, Guoxiang Cai, Minghe Wang, Hongtu Zheng, Lu Wang, Xinxiang Li, Sanjun Cai, Ye Xu

Review Article

Common applications of next-generation sequencing technologies in genomic research
Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis
Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Review Articles

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
Rositsa Dueva, George Iliakis
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer
Deep Kwatra, Anand Venugopal, Shrikant Anant
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Historical perspective and evolution of charged particle beam therapy
Huan Giap, Bosco Giap
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Role of NBS1 in DNA damage response and its relationship with cancer development
Yuichiro Saito, Hiroko Fujimoto, Junya Kobayashi
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Proton therapy for gastrointestinal cancers
Ted C. Ling, Joseph I. Kang, Jerry D. Slater, Gary Y. Yang
Proton therapy for head and neck cancer: current applications and future directions
Alexander Lin, Samuel Swisher-McClure, Laura Bonner Millar, Maura Kirk, Caitlyn Yeager, Ali Kassaee, Boong-Keng Kevin Teo, Stephen M. Hahn
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Original Articles

Comparison of tissue characterization curves for different CT scanners: implication in proton therapy treatment planning
Chee-Wai Cheng, Li Zhao, Mark Wolanski, Qingya Zhao, Josuha James, Kate Dikeman, Michael Mills, Mei Li, Shiv P. Srivastava, Xing Qi Lu, Indra J. Das

Editorial

Focusing in on radiation induced brain injury
M. Kerry O’Banion

Original Article

A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman
Defining functional changes in the brain caused by targeted stereotaxic radiosurgery
Vipan K. Parihar, Munjal M. Acharya, Dante E. Roa, Omar Bosch, Lori-Ann Christie, Charles L. Limoli
A chain reaction approach to modelling gene pathways
Gary C. Cheng, Dung-Tsa Chen, James J. Chen, Seng-jaw Soong, Coral Lamartiniere, Stephen Barnes
Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA
Takashi Kon, Xiuwu Zhang, Qian Huang, Zhonghui Yang, Shanling Liu, Bin Yan, Fang Li, He Wang, Chuan-Yuan Li
Identification of cancer mechanisms through computational systems modeling
Zhen Qi, Eberhard O. Voit
A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman

Review Article

Integrative clustering methods for high-dimensional molecular data
Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley
Sparse principal component analysis in cancer research
Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen
Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications
Louis Dubeau
Cancer biomarker discovery and validation
Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida
The promise and challenge of ovarian cancer models
Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Review Articles

New developments in treatment planning and verification of particle beam therapy
Reinhard W. Schulte, Andrew J. Wroe
Externally modulated theranostic nanoparticles
Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi
Intestinal stem cell injury and protection during cancer therapy
Jian Yu
Cancer stem cells in glioma: challenges and opportunities
Jialiang Wang, Yufang Ma, Michael K. Cooper
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou
Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis
Chang-Lung Lee, Jordan M. Blum, David G. Kirsch
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
DNA double strand break repair via non-homologous end-joining
Anthony J. Davis, David J. Chen
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation
Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase
Lijian Shao, Lixian Wu, Daohong Zhou
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis
Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
Improving chemoradiotherapy with nanoparticle therapeutics
Michael Joseph Eblan, Andrew Zhuang Wang
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Molecular mechanisms involved in tumor repopulation after radiotherapy
Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li
Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules
Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy
Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar
Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma
Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients
Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Original Article

Statistical strategies for microRNAseq batch effect reduction
Yan Guo, Shilin Zhao, Pei-Fang Su, Chung-I Li, Fei Ye, Charles R. Flynn, Yu Shyr

Original Article

Frameless single-isocenter intensity modulated stereotactic radiosurgery for simultaneous treatment of multiple intracranial metastases
Steven K. M. Lau, Xiao Zhao, Ruben Carmona, Erik Knipprath, Daniel R. Simpson, Sameer K. Nath, Gwe-Ya Kim, Jona A. Hattangadi, Clark C. Chen, Kevin T. Murphy

Below are the latest Translational Cancer Research articles published online ahead of print publication.

Editorial


Original Article


Review Article

Axillary lymph node surgical treatment
Daniela Andreina Terribile, Cristina Accetta, Sabatino D’Archi, Ida Paris, Danilo Di Giorgio, Giorgia Garganese, Simona Maria Fragomeni, Riccardo Masetti

Perspective


Letter to the Editors

Multiscale modeling of glioblastoma
Huaming Yan, Mónica Romero-López, Lesly I. Benitez, Kaijun Di, Hermann B. Frieboes, Christopher C. W. Hughes, Daniela A. Bota, John S. Lowengrub

Case report


Mini-Review