Article Abstract

Immunohistochemical findings in small cell neuroendocrine carcinoma of the cervix: a report of two cases

Authors: Hongrun Zhou, Lin Tao, Dongdong Chen, Ruijuan Gao, Lili Zhao, Ganxiong Li, Hongzhi Chen, Yan Ren, Xiaoyu Li, Yixun Wang, Lijuan Pang


Small cell carcinoma of the cervix (SCCC) is a rare and extremely aggressive malignancy with a poor prognosis. Owing to a lack of specific symptoms and low prevalence, the diagnosis of SCCC is a significant problem. Herein, the clinicopathological features, treatment, and prognosis are described for 2 cases of SCCC. The patients presented with spontaneous vaginal bleeding and post-coital spotting. Following a series of examinations, combined with clinical history, the 2 patients were diagnosed with SCCC. We also present a retrospective case study focusing on important, recently described, uncommon findings in gynecological tumors. The clinicopathological manifestations, diagnosis, and treatment are also discussed.