Article Abstract

Immunohistochemical findings in small cell neuroendocrine carcinoma of the cervix: a report of two cases

Authors: Hongrun Zhou, Lin Tao, Dongdong Chen, Ruijuan Gao, Lili Zhao, Ganxiong Li, Hongzhi Chen, Yan Ren, Xiaoyu Li, Yixun Wang, Lijuan Pang

Abstract

Small cell carcinoma of the cervix (SCCC) is a rare and extremely aggressive malignancy with a poor prognosis. Owing to a lack of specific symptoms and low prevalence, the diagnosis of SCCC is a significant problem. Herein, the clinicopathological features, treatment, and prognosis are described for 2 cases of SCCC. The patients presented with spontaneous vaginal bleeding and post-coital spotting. Following a series of examinations, combined with clinical history, the 2 patients were diagnosed with SCCC. We also present a retrospective case study focusing on important, recently described, uncommon findings in gynecological tumors. The clinicopathological manifestations, diagnosis, and treatment are also discussed.

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