Article Abstract

Evolving development of multi-parametric normal tissue complication probability model for liver radiotherapy

Authors: Chiao-Ling Tsai, Jason Chia-Hsien Cheng


The dosimetry model of normal tissue complication probability (NTCP) has been investigated for decades. Incorporation of imaging parameters and biomarkers into NTCP is a must in this modern era. El Naqa and colleagues developed a novel NTCP model with the incorporation of imaging and cytokine biomarkers for patients with hepatocellular carcinoma (HCC) undergoing radiotherapy (RT) (1).