This focused issue on “Energy Balance, Aging, Obesity, and Cancer” is edited by Nathan A. Berger, from Departments of Medicine, Biochemistry, Oncology, Genetics & Genome Sciences, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Dr. Berger is the Hanna-Payne Professor of Experimental Medicine and Director of the Center for Science, Health and Society at Case Western Reserve University School of Medicine. He is Professor of Medicine, Biochemistry, Oncology and Genetics and CWRU Distinguished University Professor. Dr. Berger is an active researcher whose early research focused on laboratory and translational aspects of poly (ADP-ribose) polymerase, DNA repair, stress proteins, and developmental therapeutics. His current research focuses on Transdisciplinary Studies in Energy Balance and Cancer and critical aspects of the relations between Aging, Obesity, Energy Balance and Cancer. He is co-director of the NIH funded Specialized Program on Research Excellence in Gastrointestinal Malignancies and on The Barrett’s Esophagus Research Network where he coordinates their pilot projects and career development programs. His laboratory is investigating the mechanisms by by which obesity accelerates and exercise controls cancer progression as well as development of strategies to disrupt these processes.
- Focused issue outline:
- Introduction on Energy Balance, Aging, Obesity, and Cancer
- Epigenetics, Energy Balance, Aging, and Cancer
- Impact Exercise and Nutrition on Immune System Regulation, Aging & Cancer
- Regulation of Aging and Cancer by Enhanced Environment Activation of Hypothalamic-Sympatho-Adipocyte Axis
- Nutrition, Aging, Obesity and Cancer
- Aging, Diabetes, Obesity, and Cancer
- Geriatric Effects on Body Composition, Sarcopenia and Chemotherapy Tolerance
- p16 A Biomarker of Aging and Tolerance for Cancer Therapy
- Effect of Functional Decline in Cancer Therapy and Tolerance