Vol 4, No 1 (February 2015): Translational Cancer Research (Epithelial ovarian cancer treatment: integrating molecular targeting)

Review Article

Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications
Louis Dubeau
The promise and challenge of ovarian cancer models
Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu
Molecular targeting of low-grade serous and mucinous carcinomas of the ovary or peritoneum
David M. Gershenson
Therapeutic implications for ovarian cancer emerging from the Tumor Cancer Genome Atlas
Claire Verschraegen, Karen Lounsbury, Alan Howe, Marc Greenblatt
Modulation of intraperitoneal (IP) chemotherapy in ovarian cancer
Maryann Kwa, Danielle Jandial
Targeting angiogenesis: vascular endothelial growth factor and related signaling pathways
Amanda L. Jackson, Sara Madison Davenport, Thomas J. Herzog, Robert L. Coleman
Targeting DNA repair: poly (ADP-ribose) polymerase inhibitors
Melissa K. Frey, Bhavana Pothuri
Targeting the PI3K/AKT/mTOR pathway in ovarian cancer
Fernanda Musa, Robert Schneider
EGFR and HER2: is there a role in ovarian cancer?
Eleonora Teplinsky, Franco Muggia
Targeting the folate receptor for the treatment of ovarian cancer
Robert J. Lutz
Integrating targeted drugs with taxanes and platinums: opportunities and challenges
David Kudlowitz, Eleonora Teplinsky, Franco Muggia


The focused issue “Epithelial ovarian cancer treatment: integrating molecular targeting” was commissioned by the editorial office, Translational Cancer Research without any sponsorship or funding. Franco Muggia and Eleonora Teplinsky served as the unpaid Guest Editors for the focused issue.