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Original Article

Distribution of HLA-A alleles and its relation to clinical outcome in Uyghur and Han patients with advanced squamous cell cervical cancer in Xinjiang, China
Mayinuer Alifu, Xuemei Chang, Gulina Kuerban, Yaning Feng, Xuan Yao, Yanchun Peng, Yunhui Hu, Tao Dong, Ruozheng Wang
Genomic alterations across six hepatocellular carcinoma cell lines by panel-based sequencing
Yangjing Zhao, Yanhui Chen, Ying Hu, Jianghua Wang, Xingwang Xie, Gaixia He, Hongsong Chen, Qixiang Shao, Hui Zeng, Henghui Zhang
In vitro and in vivo suppression of hepatocellular carcinoma by Amorphophallus konjac tuber through regulation of survivin and bax
Lei Pan, Peifeng Chen
cMET-N375S germline mutation is associated with poor prognosis of melanoma in Chinese patients
Tian-Xiao Xu, Si-Fan Yu, Meng Ma, Jie Dai, Zhi-Hong Chi, Lu Si, Xi-Nan Sheng, Chuan-Liang Cui, Yan Kong, Jun Guo
Risks of second primary malignancies among Chinese cancer survivors at a single center during 2002–2016
Peiyuan Dong, Linan Deng, Xing Xin, Dan Luo, Zhaojun Liu, Hanying Sun, Fankai Meng
Basic characteristics and therapy regimens for colorectal squamous cell carcinoma
Jinxin Shi, Yu Sun, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Dehao Yu, Xinger Lv, Xin Zhou, Zhenning Wang
Microwave ablation of ex vivo human undifferentiated pleomorphic sarcoma
Zhen-Jie Wu, Wei-Hua Chen, Ju-Liang He, Bin Liu, Hao Mo, Jian Guan, Xiang Lin, Zhen-Chao Yuan
The overexpression of cytochrome c oxidase subunit 6C activated by Kras mutation is related to energy metabolism in pancreatic cancer
Jigang Yang, Jun Liu, Shuxin Zhang, Yuanyuan Yang, Jianhua Gong
Prognostic values of preoperative NLR and PLR in patients with laryngeal squamous cell carcinoma
Xiu-Ping Tu, Tian Tian, Liang-Si Chen, Xiao-Ning Luo, Zhong-Ming Lu, Si-Yi Zhang, Shao-Hua Chen
Microarray screening for key genes and prognosis factors in interferon regulatory factor 1-silenced ovarian cancer SKOV-3 cells
Juan Liu, Zequn Liu, Fang Fu, Ru Li, Tingying Lei, Qiong Deng, Lushan Li, Dan Yang, Fang Wang, Can Liao
Characterization of genomic clones using circulating tumor DNA in patients with hepatocarcinoma
Yan Sun, Rui Meng, Zheng-Yu Cheng, Chen Fan, Xiao-Ming Wei, Yun Yang, Gang Wu, Karsten Kristiansen, Jun Xue
Upregulation of programmed death ligand 1 and epidermal growth factor receptor is associated with poor prognosis in gastric cancer
Wei Wei, Dachuan Zhang, Bin Xu, Jingting Jiang, Changping Wu
Prognostic factors and outcomes of osseous chondrosarcoma after surgery: the 2004–2014 Surveillance, Epidemiology, and End Results database study
Chun-Hui Chen, Dong Chen, Zhong-Ke Lin, Hui Xu, Jing-Wei Zheng, Yan Lin, Wen-Fei Ni, Xiang-Yang Wang, Hua Chen, Zhi-Guang Qiao, Ai-Min Wu
Prognostic value of LAMP1 in surgically resected esophageal squamous cell carcinoma
Wei Wang, Yujing Zhang, Yingze Xu, Xiaobei Zhang, Ming Ma, Guoan Zhang, Jian Huang
WASF3 is associated with tumour invasiveness and confers a poor prognosis in human gastric cancer
Ying Hu, Guo An, Yi-Qiang Liu, Yi-Xue Wang, Li-Jie Song, Meng Chen, Jun Zhang
Estrogen receptor β and estrogen receptor α36 predict differential outcome of patients with breast cancer
Zi-Han Sun, Ying Hu, Minghao Wang, Xu-Gang Hu, Youhong Cui, Jun Jiang
Effects of three common polymorphisms in microRNAs on lung cancer risk: a meta-analysis
Xiaoting Lv, Zhigang Cui, Zhihua Yin, Weili Yang, Hang Li, Baosen Zhou
Pharmacologically relevant concentrations of berberine transiently stimulate dihydrotestosterone-inducible androgen receptor-mediated luciferase activity in human prostate cancer cells
Ondrej Zenata, Zdenek Dvorak, Radim Vrzal
Investigation of an optimal lysis method for the study of thymus and thymoma by mass spectrometry-based proteomics
Qiangling Sun, Xin Ku, Ning Xu, Xuefei Zhang, Wei Yan, Wentao Fang
The association of interleukin-6 gene polymorphism and risk of colorectal cancer in Chinese patients
Shuwei Wang, Zhongyang Ding, Jiandong Tang, Gan Li
Dihydropyrimidine dehydrogenase overexpression correlates with potential resistance to 5-fluorouracil-based treatment in head and neck squamous cell carcinoma
Shoko Shimada, Daisuke Sano, Hiroshi Hyakusoku, Takashi Hatano, Hideaki Takahashi, Yasuhiro Isono, Kae Sawakuma, Kentaro Takada, Koji Okudela, Nobuhiko Oridate
Efficacy and safety of apatinib in patients with metastatic colorectal cancer refractory to standard therapies
Wangxia Lv, Meiqin Yuan, Yazheng Zhao, Zhong Shi, Yunshan Yang, Haijun Zhong
Primary hepatic neuroendocrine tumors: retrospective analysis of seven cases and literature review
Qichen Chen, Xiao Chen, Haizhen Lu, Hong Zhao, Jianjun Zhao, Xinyu Bi, Dongbing Zhao, Yihebali Chi, Zhiyu Li, Zhen Huang, Yefan Zhang, Jianguo Zhou, Jianqiang Cai
Upregulated GP73 expression and downregulated NLRP3 expression in liver cancer tissues correlate with patient’s survival
Yixin Mao, Huayu Yang, Lejia Sun, Yilei Mao, Xianju Qin

Review Article

Common applications of next-generation sequencing technologies in genomic research
Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis
Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Review Articles

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
Rositsa Dueva, George Iliakis
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer
Deep Kwatra, Anand Venugopal, Shrikant Anant
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Historical perspective and evolution of charged particle beam therapy
Huan Giap, Bosco Giap
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Role of NBS1 in DNA damage response and its relationship with cancer development
Yuichiro Saito, Hiroko Fujimoto, Junya Kobayashi
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Proton therapy for gastrointestinal cancers
Ted C. Ling, Joseph I. Kang, Jerry D. Slater, Gary Y. Yang
Proton therapy for head and neck cancer: current applications and future directions
Alexander Lin, Samuel Swisher-McClure, Laura Bonner Millar, Maura Kirk, Caitlyn Yeager, Ali Kassaee, Boong-Keng Kevin Teo, Stephen M. Hahn
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Original Articles

Comparison of tissue characterization curves for different CT scanners: implication in proton therapy treatment planning
Chee-Wai Cheng, Li Zhao, Mark Wolanski, Qingya Zhao, Josuha James, Kate Dikeman, Michael Mills, Mei Li, Shiv P. Srivastava, Xing Qi Lu, Indra J. Das

Editorial

Focusing in on radiation induced brain injury
M. Kerry O’Banion

Original Article

A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman
Defining functional changes in the brain caused by targeted stereotaxic radiosurgery
Vipan K. Parihar, Munjal M. Acharya, Dante E. Roa, Omar Bosch, Lori-Ann Christie, Charles L. Limoli
A chain reaction approach to modelling gene pathways
Gary C. Cheng, Dung-Tsa Chen, James J. Chen, Seng-jaw Soong, Coral Lamartiniere, Stephen Barnes
Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA
Takashi Kon, Xiuwu Zhang, Qian Huang, Zhonghui Yang, Shanling Liu, Bin Yan, Fang Li, He Wang, Chuan-Yuan Li
Identification of cancer mechanisms through computational systems modeling
Zhen Qi, Eberhard O. Voit
A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman

Review Article

Integrative clustering methods for high-dimensional molecular data
Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley
Sparse principal component analysis in cancer research
Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen
Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications
Louis Dubeau
Cancer biomarker discovery and validation
Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida
The promise and challenge of ovarian cancer models
Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Review Articles

New developments in treatment planning and verification of particle beam therapy
Reinhard W. Schulte, Andrew J. Wroe
Externally modulated theranostic nanoparticles
Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi
Intestinal stem cell injury and protection during cancer therapy
Jian Yu
Cancer stem cells in glioma: challenges and opportunities
Jialiang Wang, Yufang Ma, Michael K. Cooper
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou
Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis
Chang-Lung Lee, Jordan M. Blum, David G. Kirsch
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
DNA double strand break repair via non-homologous end-joining
Anthony J. Davis, David J. Chen
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation
Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase
Lijian Shao, Lixian Wu, Daohong Zhou
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis
Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
Improving chemoradiotherapy with nanoparticle therapeutics
Michael Joseph Eblan, Andrew Zhuang Wang
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Molecular mechanisms involved in tumor repopulation after radiotherapy
Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li
Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules
Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy
Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar
Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma
Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients
Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Original Article

Statistical strategies for microRNAseq batch effect reduction
Yan Guo, Shilin Zhao, Pei-Fang Su, Chung-I Li, Fei Ye, Charles R. Flynn, Yu Shyr

Original Article

Frameless single-isocenter intensity modulated stereotactic radiosurgery for simultaneous treatment of multiple intracranial metastases
Steven K. M. Lau, Xiao Zhao, Ruben Carmona, Erik Knipprath, Daniel R. Simpson, Sameer K. Nath, Gwe-Ya Kim, Jona A. Hattangadi, Clark C. Chen, Kevin T. Murphy

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