About tcr

Manuscript Submission

AME Editing Service

Reprint & Permission

Advertising

Contact us

Original Article

Identification of unique microRNAs associated with pancreatic cancer radioresistance using deep sequencing
Si-Liang Wang, Ya-Jun Wang, Si-Meng Wu, Zhe Yuan, Hong-Mei Du, Xue Liu, Xi-Ke Zhu
Interleukin-17 inhibits the growth of oral squamous cell carcinoma by promoting the differentiation of T helper 17 cells
Yipeng Ren, Juntao Ma, Tong Wang, Rongfa Bu, Xiangpan Kong, Yueyi Shi, Lei Zhang
Identification of potential therapeutic targets in hepatocellular carcinoma using an integrated bioinformatics approach
Qinfeng Huang, Junhong Li, Ailing Wei
Up to 5 years outcomes following intraoperative radiotherapy for early breast cancer
Laurence Bauwens Patas d’Illiers, Frédéric Lafay, Christelle Faure, Sophie Klingler, Elodie Pleynet, Séverine Racadot
Clinicopathologic correlation of endometrial stromal sarcomas: a retrospective study of 42 cases
Fengjie Wang, Yongfen Yi, Yi Luo, Jing Chen
Therapeutic proton irradiation results in apoptosis and caspase-3 activation in human peripheral blood lymphocytes
Justyna Miszczyk, Kamila Rawojć, Anna Maria Borkowska, Agnieszka Panek, Jan Swakoń, Aleksander Gałaś, Mansoor M. Ahmed, Pataje G. S. Prasanna
Analysis of prognostic factors, including the incidence of second primary cancer, in patients with early stage laryngeal squamous cell carcinoma treated by radiation-based therapy
Kaname Sato, Kenichiro Yabuki, Daisuke Sano, Yasuhiro Arai, Yoshihiro Chiba, Teruhiko Tanabe, Goshi Nishimura, Masaharu Hata, Nobuhiko Oridate
Overexpressed miR-128a inhibits the proliferation of laryngeal cancer cells
Guang-Lun Wan, Hui Chen, Liang Zhou, Jia-Meng Huang
The targeting of endoglin on vascular endothelial cells affects the infiltration of M2 macrophages into the breast cancer microenvironment by modulating the interleukin-6 (IL-6) level
Long Zhang, Bin Yang, Xiaoli Li, Yunjing Zhang, Jinping Zhao, Wenbin Wang, Xiaohui Yu, Zhenhua Zhai, Hongzhi Sun
The efficacy of postoperative radiotherapy for locally advanced rectal cancer without neoadjuvant therapy
Dehao Yu, Yu Wang, Yongxi Song, Peng Gao, Jingxu Sun, Xiaowan Chen, Yaoyuan Hu, Zhenning Wang
A radiomics nomogram for preoperatively predicting prognosis of patients in hepatocellular carcinoma
Jie Peng, Xiaolong Qi, Qifan Zhang, Zhijiao Duan, Yikai Xu, Jing Zhang, Yanna Liu, Jie Zhou, Li Liu
Huaier extract exerts immunomodulatory effects by regulating serum cytokines in breast cancer
Li Zhang, Ning Zhang, Xinyu Qu, Yaming Li, Qifeng Yang
The TGF-β-regulated X-inactive specific transcript inhibits papillary thyroid cancer migration and invasion
Yanlu Xin, Xiao Sun, Jingwei Chi, Wei Zhang, Yangang Wang, Shihua Zhao
A novel nanoprobe-based assay for detecting K-ras mutations in plasma and stool samples from patients with pancreatic cancer: value in diagnosis and prognosis evaluation
Fei Chen, Xiao-Guang Wang, Li-Feng Qi, Juan-Fen Mo, Zheng-Xiang Zhong
Use of peripheral lymphocytes and support vector machine for survival prediction in breast cancer patients
Fang Bai, Chuanchao Wei, Peng Zhang, Dexi Bi, Meixin Ge, Qing Chen, Yijun Jia, Yunshu Lu, Kejin Wu
Therapeutic potential of molecular hydrogen in ovarian cancer
Lei Shang, Fei Xie, Jiala Li, Yating Zhang, Mengyu Liu, Pengxiang Zhao, Xuemei Ma, Tyler W. Lebaron
Clinical characteristics and prognostic factors of esophageal carcinoma associated with multiple primary carcinomas: a report of 268 cases
Zhining Yang, Dongjie Zhou, Qingxin Cai, Mei Li, Derui Li, Zhixiong Lin
Prognosis and efficiency of adjuvant therapy in resected colon signet-ring cell carcinoma
Jingxu Sun, Xin Wang, Peng Gao, Yongxi Song, Xiaowan Chen, Yu Sun, Dehao Yu, Xinger Lv, Zhenning Wang
Expression and clinical significance of negative costimulatory molecules B7-H1, B7-H3 and B7-H4 in the process of colorectal cancer’s evolution
Zhichao Qiu, Jingyi Wu, Yan Wang, Fang Wang, Xiaosong Ge, Xingxiang Liu, Xiaowei Qi, Dong Hua, Yong Mao
The expression and clinicopathological significance of CD56, CDX2, and LRP16 in intrahepatic cholangiocarcinoma
Zhanbo Wang, Haowen Tang, Jing Yuan, Xin Song, Zhigang Song, Po Zhao
Metformin prolonged the survival of diffuse large B-cell lymphoma and grade 3b follicular lymphoma patients responding to first-line treatment with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone: a prospective phase II clinical trial
Xing Fan, Hui-Juan Zhong, Bing-Bing Zhao, Bin-Shen Ou Yang, Yan Zhao, Jing Ye, Yi-Ming Lu, Chao-Fu Wang, Hong Xiong, Sai-Juan Chen, Anne Janin, Li Wang, Wei-Li Zhao
SLC5A12 is a prognostic marker in head and neck squamous cell carcinoma
Yongbing Yan, Yue Qi, Zhenxing Zhang, Jieying Li, Qicheng Zhang, Wei Wang, Huijun Yue, Jun Lu, Jing Chen, Miao Gu
ND4 mutations are more prevalent in patients with acute myeloid leukemia of M2 morphology
Min Xu, Xiao-Li Zhao, Yu Zhu, Wen-Yi Shen, Ming Hong, Guang-Sheng He, Han Zhu, Yao-Yu Chen, Si-Xuan Qian, Jian-Yong Li, Chun Qiao
Relationships of kin17 protein expression with clinical features and prognosis of colorectal cancer
Liqin Ruan, Qunguang Jiang, Haitao Zhang
IQGAP1 plays an important role in the tumorigenesis and invasion of papillary thyroid cancer
Fada Xia, Zhuolu Wang, Yong Chen, Bo Jiang, Wenlong Wang, Xinying Li
Hearing outcomes between multi-session and single-session radiosurgery for vestibular schwannoma: a single center study
Xuqun Tang, Mingzhe Zheng, Hailiang Tang, Hanfeng Wu, Nan Zhang, Jiazhong Dai, Li Pan
P53 introduction enhances chemotherapy-induced apoptosis in Hela cells
Wei Sun, Xiangxuan Zhao, Zaiming Lu, Qiyong Guo
Enhanced recovery program in liver resection surgery: a single center experience
Yuan Ding, Zhenzhen Gao, Zhongquan Sun, Qiyi Zhang, Bo Zhou, Zhiwei Li, Wenyan Zhang, Yuancong Jiang, Xiangying Zhang, Guomei Ge, Matteo Ravaioli, Chris Jones, Sheng Yan, Weilin Wang, written on behalf of the AME Liver Surgery Collaborative Group

Review Article

Prognostic role of neutrophil-to-lymphocyte ratio in unresectable hepatocellular cancer patients treated with trans-arterial chemoembolization
Weiyu Xu, Jianping Xiong, Jianzhen Lin, Junyu Long, Yi Bai, Yongchang Zheng, Hongyu Xue, Xinting Sang, Haitao Zhao
Role of the androgen signaling axis in genitourinary malignancies
Brian M. Shinder, Adam Shupe, Geun Taek Lee, Mark N. Stein, Isaac Y. Kim, Eric A. Singer

Review Article

Common applications of next-generation sequencing technologies in genomic research
Chien-Yueh Lee, Yu-Chiao Chiu, Liang-Bo Wang, Yu-Lun Kuo, Eric Y. Chuang, Liang-Chuan Lai, Mong-Hsun Tsai

Meta-Analysis

Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: a meta-analysis
Ping Zhan, Qian Qian, Benjamin Wan, Tristan D. Yan, Li-Ke Yu

Review Articles

Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
Rositsa Dueva, George Iliakis
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer
Deep Kwatra, Anand Venugopal, Shrikant Anant
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Historical perspective and evolution of charged particle beam therapy
Huan Giap, Bosco Giap
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Role of NBS1 in DNA damage response and its relationship with cancer development
Yuichiro Saito, Hiroko Fujimoto, Junya Kobayashi
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Proton therapy for gastrointestinal cancers
Ted C. Ling, Joseph I. Kang, Jerry D. Slater, Gary Y. Yang
Proton therapy for head and neck cancer: current applications and future directions
Alexander Lin, Samuel Swisher-McClure, Laura Bonner Millar, Maura Kirk, Caitlyn Yeager, Ali Kassaee, Boong-Keng Kevin Teo, Stephen M. Hahn
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou

Original Articles

Comparison of tissue characterization curves for different CT scanners: implication in proton therapy treatment planning
Chee-Wai Cheng, Li Zhao, Mark Wolanski, Qingya Zhao, Josuha James, Kate Dikeman, Michael Mills, Mei Li, Shiv P. Srivastava, Xing Qi Lu, Indra J. Das

Editorial

Focusing in on radiation induced brain injury
M. Kerry O’Banion
Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic
Naomi Lomeli, Daniela A. Bota
Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma
David C. Binder, Erik Ladomersky, Alicia Lenzen, Lijie Zhai, Kristen L. Lauing, Sebastian D. Otto-Meyer, Rimas V. Lukas, Derek A. Wainwright
Gut microbes modulate host response to immune checkpoint inhibitor cancer immunotherapy
Kebin Liu, Chunwan Lu
New light on the pancreatic cyst conundrum
Nathan A. Berger

Original Article

A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman
Defining functional changes in the brain caused by targeted stereotaxic radiosurgery
Vipan K. Parihar, Munjal M. Acharya, Dante E. Roa, Omar Bosch, Lori-Ann Christie, Charles L. Limoli
A chain reaction approach to modelling gene pathways
Gary C. Cheng, Dung-Tsa Chen, James J. Chen, Seng-jaw Soong, Coral Lamartiniere, Stephen Barnes
Oncolytic virus-mediated tumor radiosensitization in mice through DNA-PKcs-specific shRNA
Takashi Kon, Xiuwu Zhang, Qian Huang, Zhonghui Yang, Shanling Liu, Bin Yan, Fang Li, He Wang, Chuan-Yuan Li
Identification of cancer mechanisms through computational systems modeling
Zhen Qi, Eberhard O. Voit
A recursively partitioned mixture model for clustering time-course gene expression data
Devin C. Koestler, Carmen J. Marsit, Brock C. Christensen, Karl T. Kelsey, E. Andres Houseman
Matrix metalloproteinase (MMP) and immunosuppressive biomarker profiles of seven head and neck squamous cell carcinoma (HNSCC) cell lines
Amber M. Bates, Maria Paula Gomez Hernandez, Emily A. Lanzel, Fang Qian, Kim A. Brogden

Review Article

Integrative clustering methods for high-dimensional molecular data
Prabhakar Chalise, Devin C. Koestler, Milan Bimali, Qing Yu, Brooke L. Fridley
Sparse principal component analysis in cancer research
Ying-Lin Hsu, Po-Yu Huang, Dung-Tsa Chen
Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications
Louis Dubeau
Cancer biomarker discovery and validation
Nicolas Goossens, Shigeki Nakagawa, Xiaochen Sun, Yujin Hoshida
The promise and challenge of ovarian cancer models
Noor Hasan, Anders W. Ohman, Daniela M. Dinulescu

Perspective

Circular RNAs and competing endogenous RNA (ceRNA) networks
Apratim Mitra, Karl Pfeifer, Ki-Sun Park

Review Articles

New developments in treatment planning and verification of particle beam therapy
Reinhard W. Schulte, Andrew J. Wroe
Externally modulated theranostic nanoparticles
Cordula Urban, Alexander S. Urban, Heather Charron, Amit Joshi
Intestinal stem cell injury and protection during cancer therapy
Jian Yu
Cancer stem cells in glioma: challenges and opportunities
Jialiang Wang, Yufang Ma, Michael K. Cooper
Tumor microenvironment and nanotherapeutics
Meenakshi Upreti, Amar Jyoti, Pallavi Sethi
Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury
Lijian Shao, Yingying Wang, Jianhui Chang, Yi Luo, Aimin Meng, Daohong Zhou
Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis
Chang-Lung Lee, Jordan M. Blum, David G. Kirsch
DNA ligases as therapeutic targets
Alan E. Tomkinson, Timothy R.L. Howes, Nathaniel E. Wiest
DNA damage tolerance: a double-edged sword guarding the genome
Gargi Ghosal, Junjie Chen
DNA double strand break repair via non-homologous end-joining
Anthony J. Davis, David J. Chen
DNA crosslinking damage and cancer - a tale of friend and foe
Yaling Huang, Lei Li
Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation
Dev Kumar Chatterjee, Tatiana Wolfe, Jihyoun Lee, Aaron P Brown, Pankaj Kumar Singh, Shanta Raj Bhattarai, Parmeswaran Diagaradjane, Sunil Krishnan
MDM2 and MDMX: alone and together in regulation of p53
Miriam Shadfan, Vanessa Lopez-Pajares, Zhi-Min Yuan
Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase
Lijian Shao, Lixian Wu, Daohong Zhou
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
Feng-Ming Hsu, Shichuan Zhang, Benjamin P.C. Chen
SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis
Seong-Hoon Park, Yuming Zhu, Ozkan Ozden, Hyun-Seok Kim, Haiyan Jiang, Chu-Xia Deng, David Gius, Athanassios Vassilopoulos
Normal tissue protection for improving radiotherapy: where are the Gaps?
Pataje G.S. Prasanna, Helen B. Stone, Rosemary S. Wong, Jacek Capala, Eric J. Bernhard, Bhadrasain Vikram, C. N. Coleman
Improving chemoradiotherapy with nanoparticle therapeutics
Michael Joseph Eblan, Andrew Zhuang Wang
Gold nanoparticles in radiation research: potential applications for imaging and radiosensitization
Jay F. Dorsey, Lova Sun, Daniel Y. Joh, Alon Witztum, Ajlan Al Zaki, Gary D. Kao, Michelle Alonso-Basanta, Stephen Avery, Andrew Tsourkas, Stephen M. Hahn
Molecular mechanisms involved in tumor repopulation after radiotherapy
Wooi-Loon Ng, Qian Huang, Xinjian Liu, Mary Zimmerman, Fang Li, Chuan-Yuan Li
Efficacy of combination treatment modalities for intermediate and advanced hepatocellular carcinoma: intra-arterial therapies, sorafenib and novel small molecules
Julio A. Gutierrez, Robert G. Gish

Original Articles

Third generation gold nanoplatform optimized for radiation therapy
Rajiv Kumar, Houari Korideck, Wilfred Ngwa, Ross I. Berbeco, G. Mike Makrigiorgos, Srinivas Sridhar
Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma
Tzu-Hung Hsiao, Hung-I Harry Chen, Jo-Yang Lu, Pei-Ying Lin, Charles Keller, Sarah Comerford, Gail E. Tomlinson, Yidong Chen

Research Highlights

A balancing act for breast cancer? Everolimus for hormone receptor positive patients
Stephanie B Wheeler, Katherine Reeder-Hayes, Anne-Marie Meyer

Original Article

Statistical strategies for microRNAseq batch effect reduction
Yan Guo, Shilin Zhao, Pei-Fang Su, Chung-I Li, Fei Ye, Charles R. Flynn, Yu Shyr

Original Article

Frameless single-isocenter intensity modulated stereotactic radiosurgery for simultaneous treatment of multiple intracranial metastases
Steven K. M. Lau, Xiao Zhao, Ruben Carmona, Erik Knipprath, Daniel R. Simpson, Sameer K. Nath, Gwe-Ya Kim, Jona A. Hattangadi, Clark C. Chen, Kevin T. Murphy

Below are the latest Translational Cancer Research articles published online ahead of print publication.

Case Report


Editorial


Original Article


Review Article



Case report